Steroid saponins from Paris polyphylla Sm.-supplement.

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In vitro and in vivo anticancer activity of steroid saponins of Paris polyphylla var. yunnanensis.

AIM To confirm the anticancer activity of steroid saponins isolated from the rhizome of Paris polyphylla var. yunnanensis and evaluate the structure-activity relationships of these steroid saponins in vitro and in vivo . MATERIALS AND METHODS Eight known steroid saponins were isolated from the rhizome of Paris polyphylla . The LA795 lung adenocarcinoma cell line from mice was chosen to evalua...

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In-vitro Antitumor Activity and Antifungal Activity of Pennogenin Steroidal Saponins from paris Polyphylla var. yunnanensis

Paris polyphylla Smith var. yunnanensis, has been used in traditional Chinese medicine for its antibiotic and anti-inflammatory properties; in addition it has been used to cure liver cancer in particular. In this current study, β-ecdysterone (1) and three pennogenin steroidal saponins (2-4) were isolated from the EtOH extract of Paris polyphylla var. yunnanensis, and then tested for their antit...

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In-vitro Antitumor Activity and Antifungal Activity of Pennogenin Steroidal Saponins from paris Polyphylla var. yunnanensis

Paris polyphylla Smith var. yunnanensis, has been used in traditional Chinese medicine for its antibiotic and anti-inflammatory properties; in addition it has been used to cure liver cancer in particular. In this current study, β-ecdysterone (1) and three pennogenin steroidal saponins (2-4) were isolated from the EtOH extract of Paris polyphylla var. yunnanensis, and then tested for their antit...

متن کامل

In-vitro Antitumor Activity and Antifungal Activity of Pennogenin Steroidal Saponins from paris Polyphylla var. yunnanensis

Paris polyphylla Smith var. yunnanensis, has been used in traditional Chinese medicine for its antibiotic and anti-inflammatory properties; in addition it has been used to cure liver cancer in particular. In this current study, β-ecdysterone (1) and three pennogenin steroidal saponins (2-4) were isolated from the EtOH extract of Paris polyphylla var. yunnanensis, and then tested for their antit...

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Steroidal Saponins from Paris Polyphylla Suppress Malignancy of Human Lung Cancer A549 Cells

Lung cancer is the leading causes of cancer death worldwide (Siegel et al., 2014), mainly due to the difficulty of early diagnosis and the highly metastatic potential, which has being the hotspot of lung cancer research (Li et al., 2014). In fact, the metastasis has already developed before the diagnosis of lung cancer in most cases, for example, approximately 30 to 40% of patients with advance...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1982

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.30.712